NWD Jansen et al. Arthritis and Rheumatism (2007) Vol.56#1 p 199 – 207
“Exposure of Human Cartilage Tissue to Low Concentrations of Blood for a Short Period of Time Leads to Prolonged Cartilage Damage”
The above mechanism could perhaps provide a non-psychosocial explanation for chronic neck pain following for example, whiplash neck injury. Osteoarthritis could perhaps be accelerated by such an injury. However, it is surprising that initial injury severity is not predictive of outcome after one year; if the above mechanism is valid this is what would be expected.